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Synthesis and spectral properties of 7‐chloro‐5‐[( o ‐ and p ‐R 1 )phenyl]‐1‐R 2 ‐3 H ‐[1,4]benzodiazepin‐2‐ones
Author(s) -
Cortés Eduardo Cortés,
Martínez Isidro Ebromares,
Mellado Olivia García
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390612
Subject(s) - chemistry , yield (engineering) , stereochemistry , spectral properties , medicinal chemistry , computational chemistry , metallurgy , materials science
A series of twelve new 7‐chloro‐5‐[( o ‐ and p ‐R 1 )phenyl]‐1‐R 2 ‐3 H ‐[1,4] benzo‐diazepin‐2‐ones, which have possible pharmacological properties were synthesized. The synthesis of all the final compounds was carried out by four steps. The structure of all final products was corroborated by ir, 1 H nmr, 13 C nmr and ms, and have been obtained in 35‐94% yield.
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