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Carbocyclic galanthamine analogs: Incorporating the phenethylamine motif
Author(s) -
Treu Matthias,
Hametner Christian,
Fröhlich Johannes,
Jordis Ulrich,
Mereiter Kurt
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390609
Subject(s) - phenethylamine , chemistry , moiety , stereochemistry , ring (chemistry) , tandem , combinatorial chemistry , organic chemistry , materials science , composite material
An unnatural analog of the anti‐Alzheimer drug galanthamine bearing a phenethylamine moiety has been prepared as a racemic mixture using K 3 [Fe(CN) 6 ] induced tandem cyclization techniques in the key step to form derivatives of a novel heterocyclic ring system.