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Synthesis of novel 1,3,4‐oxadiazinane‐2‐thiones derived from (1 R ,2 S ‐ephedrine, (1 S ,2 S )‐pseudoephedrine and (1 R ,2 S )‐norephedrine
Author(s) -
Hitchcock Shawn R.,
Nora George P.,
Casper David M.,
Wiman Joseph D.,
Bentley Jeromy T.,
Stafford Carrie,
Squire Michael D.
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390546
Subject(s) - chemistry , pseudoephedrine , ephedrine , organic chemistry , medicinal chemistry , pharmacology , medicine
Abstract A several novel 1,3,4‐oxadiazinan‐2‐thiones have been synthesized by the cyclization of β‐hydrazino‐alcohols with either carbon disulfide or 1,1′‐thiocarbonyldiimidazole (TCDI).