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Reactivity of 2‐methylene‐1,3‐dicarbonyl compounds. 1,3‐dipolar cycloaddition reaction with nitrile oxide
Author(s) -
Yamauchi Masashige
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390524
Subject(s) - chemistry , nitrile , reactivity (psychology) , cycloaddition , methylene , 1,3 dipolar cycloaddition , oxide , medicinal chemistry , organic chemistry , catalysis , medicine , alternative medicine , pathology
The reaction of 2‐methylene‐1,3‐dicarbonyl compounds 1 and nitrile oxides, which were prepared from hydroxymoyl chlorides 2 with triethylamine, gave 5,5‐disubstituted 2‐isoxazolines 3 regioselectively.
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