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Synthesis and biological effects of new derivatives of benzotriazole as antimicrobial and antifungal agents
Author(s) -
AlOmran Fatima,
ElKhair Adel Abou,
Mohareb Rafat M.
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390504
Subject(s) - chemistry , benzotriazole , antimicrobial , moiety , antifungal , combinatorial chemistry , pyrimidine , pyridine , stereochemistry , triazole , organic chemistry , microbiology and biotechnology , biology
Derivatives of 2‐aminothiophene‐3‐carbonitrile, 2‐thioxopyridine‐3‐carbonitrile, 1,8‐naphthyridine‐2‐one, thieno[2,3‐ b ]pyridine‐5‐carbonitrile and thieno[2,3‐ d ]pyrimidine incorporating with a 1 H ‐benzo‐triazole moiety or 1,3,4‐thiadiazole derivatives incorporating with a benzotriazol‐1‐ylmethyl group have been synthesized and tested for antimicrobial and antifungal activities. The structures of the newly synthesized compounds have been established on the basis of their analytical and spectral data.