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Synthesis of N 4 ‐substituted[1,3,4]oxadiazinan‐2‐ones derived from norephedrine
Author(s) -
Casper David M.,
Nora George P.,
Blackburn Jennifer R.,
Bentley Jeromy T.,
Taylor Deanna C.,
Hitchcock Shawn R.
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390431
Subject(s) - chemistry , stereochemistry , medicinal chemistry , organic chemistry , computational chemistry , combinatorial chemistry
[1,3,4]‐Oxadiazinan‐2‐ones bearing substitution at the N 4 ‐position have been synthesized from norephedrine in good yield via N ‐alkylation, nitrosation, reduction and cyclization.