An efficient synthesis of a class of novel  N ‐Alkyl‐ N ‐aryl‐4‐hydroxy‐1‐methyl‐2‐oxo‐1,2‐dihydro‐3‐quinolinecarbothioamides | Zendy

Spears Glen W. | Zendy; Tsuji Kiyoshi | Zendy; Tojo Takashi | Zendy; Nishimura Hiroaki | Zendy; Ogino Takashi | Zendy

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An efficient synthesis of a class of novel N ‐Alkyl‐ N ‐aryl‐4‐hydroxy‐1‐methyl‐2‐oxo‐1,2‐dihydro‐3‐quinolinecarbothioamides

Author(s) -

Spears Glen W.,

Tsuji Kiyoshi,

Tojo Takashi,

Nishimura Hiroaki,

Ogino Takashi

Publication year - 2002

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570390427

Subject(s) - chemistry , alkyl , yield (engineering) , aryl , amide , class (philosophy) , coupling (piping) , combinatorial chemistry , stereochemistry , organic chemistry , artificial intelligence , computer science , mechanical engineering , materials science , engineering , metallurgy

The novel title compounds have been prepared in high yield by an optimized amide coupling followed by a Dieckmann cyclization. Additionally, this new route is amenable to preparative scale synthesis.

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