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Synthesis of 4,7,8a,9‐tetrahydro‐3 H ‐diimidazo‐[1,5‐ a :4′,5′‐ d ]pyridine derivatives
Author(s) -
Braña Miguel F.,
Guisado Cristina,
PérezCastells Javier,
PérezSerrano Leticia
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390228
Subject(s) - chemistry , pyridine , condensation , histamine , combinatorial chemistry , condensation reaction , medicinal chemistry , stereochemistry , organic chemistry , catalysis , medicine , physics , thermodynamics
The synthesis and evaluation of new ligands for the H 3 receptor of histamine is described. These new compounds are diimidazopyridine derivatives readily prepared by a condensation reaction of spinacine and isocyanates.