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Synthesis of the azocino[4,3‐ b ]indole core structure for the synthesis of strychnos alkaloids
Author(s) -
Ergün Yavuz,
Okay Gürol,
Patir Süleyman
Publication year - 2002
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570390212
Subject(s) - strychnos , chemistry , indole test , stereochemistry , total synthesis , combinatorial chemistry , alkaloid
The synthesis of compound 12 which has a hexahydro‐1,5‐methanoazocino[4,3‐ b ]indole structure for the synthesis of pentacyclic strychnos type alkaloids (tubifolin and tubifolidine) is described. Many new compounds 5–12 have also been synthesized.