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Inverse‐electron demand [ π 2 + σ 2 + σ 2] cycloaddition reaction of dimethyl oxaquadricyclane‐2,3‐dicarboxylate with cyclooctyne
Author(s) -
Matsumoto Kiyoshi,
Taketsuna Hiroyuki,
Kim Jong Chul,
Kakehi Akikazu
Publication year - 2001
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570380535
Subject(s) - cycloaddition , chemistry , adduct , inverse , medicinal chemistry , stereochemistry , organic chemistry , catalysis , mathematics , geometry
A first example of an inverse‐electron demand [ π 2 + σ 2 + σ 2] cycloaddition reaction of dimethyl oxaquadricyclane‐2,3‐dicarboxylate was reported: cyclooctyne underwent cycloaddition with dimethyl oxaquadricyclane‐2,3‐dicarboxylate to afford the corresponding adducts one of whose structure was confirmed by a single crystal X‐ray analysis.