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Synthesis of some novel 3,7‐dimethyl‐4 H ‐pyrazolo[5,1‐c][1,2,4]triazin‐4‐ones
Author(s) -
ElBarbary Ahmed A.,
ElBadawi Mahmoud A.,
Loksha Yasser M.
Publication year - 2001
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570380328
Subject(s) - chemistry , hydroxylamine , hydrazine (antidepressant) , oxime , hydroxylamine hydrochloride , hydrochloride , derivative (finance) , benzoyl chloride , chloride , medicinal chemistry , organic chemistry , chromatography , financial economics , economics
Some novel 3,7‐dimethyl‐6 H ‐pyrazolo[5,1‐c][1,2,4]triazin‐4‐ones were prepared (3a‐g) . Compounds 3a,b were treated with hydrazines to afford various products 7a,b, 8a,b, 9 and lla,b depending on the type of hydrazine derivative and reaction conditions. The benzoyloxyimino‐pyrazolo[5,1‐c][1,2,4]triazines (13a,b) were synthesized by refluxing of compounds 3a,b with hydroxylamine hydrochloride to afford the corresponding oxime derivatives followed by treatment with benzoyl chloride.