Synthesis of 2(3H)‐benzoxazolone and 2(3H)‐benzothiazolone derivatives as potential beta‐3‐adrenergic receptor ligands (part 2) | Zendy

Delhomel J. F. | Zendy; Yous S. | Zendy; Depreux P. | Zendy; Lesieur D. | Zendy

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Synthesis of 2(3H)‐benzoxazolone and 2(3H)‐benzothiazolone derivatives as potential beta‐3‐adrenergic receptor ligands (part 2)

Author(s) -

Delhomel J. F.,

Yous S.,

Depreux P.,

Lesieur D.

Publication year - 2001

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570380314

Subject(s) - chemistry , adrenergic receptor , beta (programming language) , lipolysis , adrenergic , receptor , stereochemistry , b2 receptor , beta 3 adrenergic receptor , pharmacology , combinatorial chemistry , biochemistry , medicine , adipose tissue , computer science , programming language , bradykinin

Adrenoceptors beta‐3‐subtype mediate lipolysis and in the search for potential beta‐3‐adrenergic receptors agonists for the treatment of obesity, we designed new arylethanolamines (structures 4, 5 ) and aryloxypropanolamines (structures 6, 7 ) derived from 2(3 H )‐benzoxazolone and 2(3 H )‐benzothiazolone.

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