Preparation of novel 2‐(benzo[ b ]furan‐2‐yl)‐1 H ‐imidazolines for photoaffinity labelling and affinity isolation of imidazoline binding | Zendy

Clews Proteins J. | Zendy; Ramsden Christopher A. | Zendy; Morgan Noel G. | Zendy

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Preparation of novel 2‐(benzo[ b ]furan‐2‐yl)‐1 H ‐imidazolines for photoaffinity labelling and affinity isolation of imidazoline binding

Author(s) -

Clews Proteins J.,

Ramsden Christopher A.,

Morgan Noel G.

Publication year - 2001

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570380237

Subject(s) - imidazoline receptor , chemistry , labelling , photoaffinity labeling , furan , stereochemistry , receptor , combinatorial chemistry , biochemistry , organic chemistry , pharmacology , medicine

The preparations of 5‐aminoefaroxan 8 and 5‐azidoefaroxan 9 , which retain the capacity to stimulate insulin secretion via the putative I 3 imidazoline receptor and are useful biological tools for affinity chromatography studies and photoaffinity labelling studies of imidazoline binding proteins, are described

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