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Studies on uracils: A facile one‐pot synthesis of pyrazolo[3,4‐ d ]pyrimidines
Author(s) -
Bhuyan P. J.,
Borah H. N.,
Lekhok K. C.,
Sandhu J. S.
Publication year - 2001
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570380230
Subject(s) - chemistry , aniline , combinatorial chemistry , organic chemistry
The reaction of 6‐hydrazino uracils 1 and nitrones 2 result in an efficient one‐pot synthesis of pyrazolo[3,4‐ d ]pyrimidines 3 in excellent yields. The isolation of the by‐product aniline from the reaction mixture supported the plausible mechanism for the formation of pyrazolo[3,4‐ d ]pyrimidines.
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