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Synthesis of lariat ether carboxylic acids based on dibenzo‐16‐crown‐5
Author(s) -
Bartsch Richard A.,
Cowey Charles L.,
Elshani Sadik,
Goo MiJa,
Huber Vincent J.,
Ivy Sheryl N.,
Johnson Russell J.,
Kim Jong Seung,
Luboch Elzbieta,
Mcdonough Joseph A.,
Pugia Michael J.,
Son Byungki,
Zhao Qiang
Publication year - 2001
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570380201
Subject(s) - chemistry , carboxylic acid , ether , crown ether , crown (dentistry) , group (periodic table) , stereochemistry , organic chemistry , medicine , ion , dentistry
Synthetic routes to forty‐seven dibenzo‐16‐crown‐5 compounds with pendant carboxylic acid groups are reported. When taken together with previously described lariat ether carboxylic acids, these new compounds provide several series with systematic structural variations including changes in the identity and attachment site(s) of one or more lipophilic groups and the length of the spacer that connects the carboxylic acid group to the polyether framework.