N ‐bromosuccinimide reactions of some heterocycles in the presence or absence of water: An overview of ring versus side chain bromination for the synthesis of important brominated heterocyclic synthons | Zendy

Goswami Shyamaprosad | Zendy; Ghosh Kumaresh | Zendy; Mukherjee Reshmi | Zendy; Adak Avijit Kumar | Zendy; Mahapatra Ajit Kumar | Zendy

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N ‐bromosuccinimide reactions of some heterocycles in the presence or absence of water: An overview of ring versus side chain bromination for the synthesis of important brominated heterocyclic synthons

Author(s) -

Goswami Shyamaprosad,

Ghosh Kumaresh,

Mukherjee Reshmi,

Adak Avijit Kumar,

Mahapatra Ajit Kumar

Publication year - 2001

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570380125

Subject(s) - synthon , chemistry , halogenation , n bromosuccinimide , ring (chemistry) , side chain , perchloric acid , reaction conditions , organic chemistry , medicinal chemistry , catalysis , polymer

Reactions of various heterocycles 1–6 with N ‐bromosuccinimide in the presence or absence of water have been studied for side chain versus ring bromination to afford some new and important heterocyclic synthons. Interestingly, the N ‐bromosuccinimide reaction in the presence of perchloric acid, a new condition, affords exclusively the new dibromo aminopicoline 1f , which is not obtained by other presently studied methods.

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