Pyridazines 92. Synthesis of dialkyldipyridazinodiazepinones as potential HIV‐1 reverse transcriptase inhibitors | Zendy

Heinisch Gottfried | Zendy; Matuszczak Barbara | Zendy; Spielmann Elisabeth | Zendy; Witvrouw Myriam | Zendy; Pannecouque Christophe | Zendy; De Clercq Erik | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Pyridazines 92. Synthesis of dialkyldipyridazinodiazepinones as potential HIV‐1 reverse transcriptase inhibitors

Author(s) -

Heinisch Gottfried,

Matuszczak Barbara,

Spielmann Elisabeth,

Witvrouw Myriam,

Pannecouque Christophe,

De Clercq Erik

Publication year - 2001

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570380117

Subject(s) - chemistry , reverse transcriptase , human immunodeficiency virus (hiv) , virology , virus , stereochemistry , biochemistry , rna , biology , gene

Two methods for the preparation of dialkylsubstituted dipyridazino[4,3‐ b :3′,4′‐ e ][1,4]diazepinones and dipyridazino[3,4‐ b :3′,4′‐ e ][1,4]diazepinones are reported. The new compounds were evaluated for their inhibitory effects against the replication of human immunodeficiency virus [HIV‐1(III B ) and HIV‐2(ROD)] in MT‐4 cells.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research