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Synthesis and stereochemical studies of 2‐substituted thiazolidine‐4‐carboxamide derivatives
Author(s) -
Refouvelet Bernard,
Pellegrini Nadia,
Robert JeanFrançois,
Crini Gregorio,
Blacque Olivier,
Kubicki Marek M.
Publication year - 2000
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570370604
Subject(s) - thiazolidine , chemistry , carboxamide , stereoselectivity , stereochemistry , combinatorial chemistry , organic chemistry , catalysis
A series of new 2‐substituted thiazolidine‐4‐carboxamide derivatives which have potentially useful immunological properties, have been synthesized in a stereoselective manner by coupling 2‐subsituted thiazolidine‐4‐carboxylic acids with amines or amino esters. The structure of these compounds was established by combination of NMR methods and by X‐ray analysis.