Synthesis of 3‐(4‐Oxo‐4 H ‐quinolizinyl‐3) and 3‐(4‐Oxo‐4 H ‐pyridino[1,2‐ a ]pyrimidinyl‐3) substituted lactic acid derivatives | Zendy

Škof Marko | Zendy; Svete Jurij | Zendy; Stanovnik Branko | Zendy

Premium

Synthesis of 3‐(4‐Oxo‐4 H ‐quinolizinyl‐3) and 3‐(4‐Oxo‐4 H ‐pyridino[1,2‐ a ]pyrimidinyl‐3) substituted lactic acid derivatives

Author(s) -

Škof Marko,

Svete Jurij,

Stanovnik Branko

Publication year - 2000

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570370405

Subject(s) - chemistry , tetrahydrofuran , ring (chemistry) , medicinal chemistry , stereochemistry , organic chemistry , solvent

A one‐step ‘ring switching’ transformation of ( S )‐3‐[(dimethylamino)methylidene]‐5‐(methoxycarbonyl)tetrahydrofuran‐2‐one ( 4 ) with 2‐pyridineacetic acid derivatives ( 5–7 ) and 2‐aminopyridines ( 8, 9 ) afforded the corresponding 3‐(4‐oxo‐4 H ‐quinolizinyl‐3)‐ (15–17) and 3‐(4‐oxo‐4 H ‐pyridino[1,2‐ a ]pyrimidinyl‐3)‐2‐hydroxypropanoates ( 18, 19 ), respectively.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research