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Synthesis of polyazacyclophane‐intercalator conjugates for combinatorial chemistry and RNA interaction studies
Author(s) -
Wang Tingmin,
An Haoyun,
Haly Becky D.,
Dan Cook P.
Publication year - 2000
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570370403
Subject(s) - chemistry , conjugated system , conjugate , intercalation (chemistry) , combinatorial chemistry , pyrene , hydrogen bond , rna , nucleophile , ring (chemistry) , supramolecular chemistry , stereochemistry , organic chemistry , molecule , polymer , catalysis , biochemistry , mathematical analysis , mathematics , gene
Anthraquinone and pyrene intercalators were conjugated to different positions of several polyaza‐pyridinocyclophanes by various linkers to provide thirteen new polyazacyclophane‐intercalator conjugates 1–13. These resulting conjugates contain two or three constrained secondary nitrogen atoms on the ring, which may serve as nucleophilic, coordinating or hydrogen‐bonding sites for combinatorial, RNA interaction and coordination studies.