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Porphyrin derivatives: Synthesis and potential applications
Author(s) -
Cavaleiro José A. S.,
Neves Maria G. P. M.,
Tomé Augusto C.,
Silva Artur M. S.,
Faustino Maria A. F.,
Lacerda Paula S.,
Silva Ana M. G.
Publication year - 2000
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570370310
Subject(s) - porphyrin , chemistry , chlorin , photodynamic therapy , reactivity (psychology) , combinatorial chemistry , photochemistry , photosensitizer , organic chemistry , medicine , alternative medicine , pathology
Porphyrin‐porphyrin and porphyrin‐chlorin dimers have been synthesized and evaluated for their photo‐physical and in vivo photodynamic therapy properties. Two of them can become potential new photosensitizers. Study of the reactivity of meso ‐tetraaryl porphyrins, as dienophiles, in Diels‐Alder transformations and as dipolarophiles in 1,3‐dipolar cycloadditions, has been undertaken. New synthetic methodologies for certain chlorin, bacteriochlorin and isobacteriochlorin type macrocycles, with potential biological significance, have been established.