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A novel and direct synthetic route to substituted 1,5‐dihydro‐4 H ‐[1]benzopyrano[4,3‐ b ]pyridine‐4,5‐diones
Author(s) -
Světlík Jan,
Prónayová Nad'A,
Hanuš Vladimír
Publication year - 2000
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570370227
Subject(s) - chemistry , pyridine , pyran , ammonium acetate , condensation , ammonium , medicinal chemistry , stereochemistry , combinatorial chemistry , organic chemistry , physics , high performance liquid chromatography , thermodynamics
The condensation of 4‐hydroxy‐6‐methyl‐2 H ‐pyran‐2‐one and substituted 2‐hydroxybenzaldehydes with ammonium acetate gave the title heterocycles. Synthesis of 1,5‐dihydro‐2‐methyl‐4 H ‐[1]naphtho‐[1′,2′:5,6]pyrano[4,3‐ b ]‐pyridine‐4,5‐dione is also described. A reaction mechanism is discussed.

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