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Synthesis of novel 5 H , 11 H ‐pyrido[2′,3′:2,3]thiopyrano[4,3‐ b ]‐indoles by fischer‐indole cyclization
Author(s) -
Da Settimo Antonio,
Marini Anna Maria,
Primofiore Giampaolo,
Da Settimo Federico,
Salerno Silvia,
La Motta Concettina,
Pardi Gianluca,
Ferrarini Pier Luigi,
Mori Claudio
Publication year - 2000
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570370224
Subject(s) - chemistry , indole test , stereochemistry
Abstract The synthesis of the title compounds 5 H , 11 H ‐pyrido[2′,3′:2,3]thiopyrano[4,3‐ b ]indoles was accomplished by the Fischer indole cyclization of some 2,3‐dihydrothiopyrano[2,3‐ b ]pyridin‐4(4 H )‐one phenylhydrazones and 7‐methyl‐2,3‐dihydrothiopyrano[2,3‐ b ]pyridin‐4(4 H )‐one phenylhydrazones. The synthesis of the new 2,3‐dihydrothiopyrano[2,3‐ b ]pyridin‐4(4 H )‐one, which was used as one of the starting compounds, is also described.