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Synthesis and conversion of 2‐(pyrazol‐1‐yl)quinoxaline 4‐oxides
Author(s) -
Kim Ho Sik,
Kwag Sam Tag,
Choi Kyung Ok,
Okamoto Yoshihisa,
Kajiwara Shinnosuke,
Fujiwara Noriko,
Kurasawa Yoshihisa
Publication year - 2000
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570370116
Subject(s) - quinoxaline , chemistry , acetylacetone , medicinal chemistry , oxide , organic chemistry
The reaction of 6‐chloro‐2‐hydrazinoquinoxaline 4‐oxide 1b with acetylacetone or benzoylacetone gave 6‐chloro‐2‐(3,5‐dimethylpyrazol‐i‐yl)quinoxaline 4‐oxide 5a or 6‐chloro‐2‐(3‐methyl‐5‐phenylpyrazol‐1‐yl)quinoxaline 4‐oxide 5b , respXectively. Compound 5a or 5b was converted into the pyrrolo[1,5‐ a ]quinoxaline 6a or 6b , triazolo[4,3‐ a ]quinoxaline 9a or 9b , and tetrazolo[1,5‐ a ]quinoxaline 10.