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A convenient method for the synthesis of six‐membered heterocyclic enaminones
Author(s) -
Puebla Pilar,
Honores Zoila,
Medarde Manuel,
Caballero Esther,
Feliciano Arturo San,
Morán Lourdes
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360445
Subject(s) - chemistry , moiety , combinatorial chemistry , organic chemistry , heterocyclic compound , reaction conditions , catalysis
Enaminones are widely employed in the synthesis of heterocycles, however heterocyclic enaminones and their use in the synthesis of more complex systems have been less studied. The reaction between 4‐chloroacetylacetate and aliphatic or aromatic 1,2‐aminoalcohols, 1,2‐aminothiols or 1,2‐diamines, yields in one pot a six‐membered 1,4‐heterocyclic system containing the enaminone moiety.