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On the reaction of meldrum's acid with N ‐trimethylsilylanilines substituted by electron withdrawing groups
Author(s) -
Roche Sandrine,
Yous Saïd,
Couturier Daniel,
Rigo Benoît
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360439
Subject(s) - chemistry , meldrum's acid , polar effect , medicinal chemistry , organic chemistry
The reaction of Meldrum's acid with silylated anilines substituted by an electron withdrawing group easily yields the corresponding N ‐phenyl malonamic acid, when the reaction is performed under high vacuum in dichlorobenzene.