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Synthesis of 2′‐[2‐(5‐benzyloxyindolyl)]propylamine derivatives
Author(s) -
Marco José L.,
Martin Gema
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360416
Subject(s) - chemistry , propylamine , monoamine oxidase , stereochemistry , combinatorial chemistry , medicinal chemistry , organic chemistry , amine gas treating , enzyme
The synthesis of some 2′‐[2‐(5‐benzyloxyindolyl)]propylamine derivatives 1–15 from 2‐(5‐benzyloxyindole)carboxyaldehyde ( 16 ) and 2‐(5‐benzyloxy‐1‐methylindole) carboxyaldehyde ( 17 ) is reported. Compounds 1–15 have been designed as potential monoamine oxidase A and B inhibitors.