Premium
Polycyclic N ‐heterocyclic compounds. 55 . A novel reaction of N ‐(5,6‐dihydro[1]benzothiepino[5,4‐ d ]pyrimidin‐4‐yl)amidine or its amide oxime derivatives with hydroxylamine
Author(s) -
Zhang YingXue,
Sasaki Kenji,
Hirota Takashi
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360335
Subject(s) - chemistry , amidine , hydroxylamine hydrochloride , oxime , ring (chemistry) , hydroxylamine , amide , pyrimidine , hydrochloride , cleavage (geology) , medicinal chemistry , nitrile , lactam , stereochemistry , organic chemistry , geotechnical engineering , fracture (geology) , engineering
Abstract The reactions of N ‐(5,6‐dihydro[1]benzothiepino[5,4‐ d ]pyrimidin‐4‐yl)amidines or its amide oxime derivatives with hydroxylamine hydrochloride under basic condition gave abnormal cyclization products via a ring cleavage of pyrimidine component accompanied with a ring closure of [1,2,4]oxadiazole.