Premium
The solid‐state michael addition of indole to 4‐arylidene‐3‐methyl‐5‐pyrazolone
Author(s) -
Li XiaoLiu,
Wang YongMei,
Matsuura Teruo,
Meng JiBen
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360320
Subject(s) - chemistry , pyrazolone , indole test , michael reaction , organic chemistry , solid state , aryl , medicinal chemistry , catalysis , alkyl
The Michael addition reactions of indole to 4‐arylidene‐3‐methyl‐1‐phenyl‐5‐pyrazolone 1 were investigated in the solid state, by which a series of new compounds, 1‐aryl‐1‐(3‐indolyl)‐1‐(3′‐methyl‐1′‐phenyl‐5′‐pyrazolon‐4′‐yl)methanes 2 , were easily obtained. This provides a feasible method of preparing novel compounds containing two heterocyclic groups at the same carbon.