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Dihydrothienopsoralens: New furocoumarins as potential photoreacting agents
Author(s) -
Zoubir B.,
Refouvelet B.,
Xicluna A.,
Aubin F.,
Humbert P.
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360230
Subject(s) - furocoumarins , chemistry , absorbance , molar absorptivity , furan , photochemistry , fluorescence , yield (engineering) , combinatorial chemistry , organic chemistry , chromatography , optics , physics , materials science , metallurgy
A series of new dihydrothienopsoralen derivatives were synthesized from 6‐hydroxybenzo[ b ]furan in four steps in good yield. These compounds were prepared as potential photosensitizing and chemotherapeutic agents for psoriasis. The spectroscopy study in also reported and showed an absorbance at λ = 364 nm and fluorescence at λ = 440 nm with high molar absorptivity, wave length used to perform the photochemical and photobiological experiments.