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Reactions of N ‐aryl‐1 H ‐benzotriazolyl‐1‐methanamines with allyl trimethylsilanes. A facile route to trialkylsilane tetrahydroquinolines
Author(s) -
Katritzky Alan R.,
Cui Xilin,
Long Qiuhe
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360207
Subject(s) - chemistry , benzotriazole , aryl , trimethylsilyl , lewis acids and bases , formaldehyde , condensation , medicinal chemistry , organic chemistry , catalysis , alkyl , physics , thermodynamics
N ‐Aryl‐1 H ‐benzotriazolyl‐1‐methanamines 1 , easily accessible from the condensation of anilines with formaldehyde and benzotriazole, undergo Lewis acid assisted reactions with allyl trimethylsilanes to give 4‐(trimethylsilyl)methyl‐1,2,3,4‐tetrahydroquinolines 2 in good to high yields.
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