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Retro‐ene reaction. V. Functionalization of 4,5‐dihalopyridazin‐6‐ones using 1‐hydroxymethyl‐4,5‐dihalopyridazin‐6‐ones as 1–0, 3‐n, 5–0 ene‐adducts
Author(s) -
Chung HyunA,
Kang YoungJin,
Chung JooWha,
Cho SuDong,
Yoon YongJin
Publication year - 1999
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570360142
Subject(s) - chemistry , ene reaction , hydroxymethyl , surface modification , adduct , medicinal chemistry , organic chemistry
Functionalization of 1‐hydroxymethyl‐4,5‐dihalopyridazin‐6‐ones via a retro‐ene reaction with some nucleophiles gave regioselectively only 5‐halo‐4‐substitutedpyridazin‐6‐ones.