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Pyrrolo[3,2‐ c ][1,2,5]benzotriazocine: A new ring system
Author(s) -
Passannanti Alessandra,
Diana Patrizia,
Barraja Paola,
Lauria Antonino,
Cirrincione Girolamo,
Mingoia Francesco
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350655
Subject(s) - chemistry , ring (chemistry) , yield (engineering) , nucleophile , pyrrole , nucleophilic substitution , medicinal chemistry , series (stratigraphy) , stereochemistry , combinatorial chemistry , organic chemistry , catalysis , materials science , metallurgy , paleontology , biology
A nucleophilic substitution reaction in the pyrrole series, achieved by a neutral nucleophile, led to the key intermediate 7 which by reduction and successive diazotization afforded the new ring system pyrrolo[3,2‐ c ][1,2,5]benzotriazocine 9 in good yield.