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Urea as leaving group in the synthesis of 3‐( tert ‐butyl)perhydro‐1,5,3‐dithiazepine
Author(s) -
Wellmar Ulf
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350653
Subject(s) - chemistry , yield (engineering) , urea , group (periodic table) , medicinal chemistry , product (mathematics) , leaving group , organic chemistry , stereochemistry , catalysis , materials science , metallurgy , geometry , mathematics
The new compound 3‐( tert ‐butyl)perhydro‐1,5,3‐dithiazepine has been synthesised from 5‐( tert‐ butyl)perhydro‐1,3,5‐triazin‐2‐one in 45% yield. In the reaction, urea acts as the leaving group being exchanged for the S‐CH 2 ‐CH 2 ‐S fragment of the product.
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