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Studies on the chemistry of thienoannelated o,n ‐ and s,n‐ containing heterocycles. 16 . Synthesis of some thieno[1,4]thiazine derivatives with potential calcium antagonistic activity
Author(s) -
Erker Thomas
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350651
Subject(s) - chemistry , thiazine , calcium , medicinal chemistry , stereochemistry , organic chemistry
Substituted thieno[1,4]thiazine derivatives have been synthesized. They are thienoanalogues of compound 3 [2], a potent cerebral protectant and calcium antagonist. Research activities concentrate on the preparation of structurally modified compounds of 3 to minimize its undesirable symptoms.