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Synthesis of pyrazolecarbonylaminopyridinecarboxamides as herbicides
Author(s) -
Parlow John J.
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350646
Subject(s) - chemistry , pyridine , regioselectivity , combinatorial chemistry , lead compound , stereochemistry , organic chemistry , biochemistry , in vitro , catalysis
Target compounds from a herbicide lead area, pyrazolecarboxamides, were selected and synthesized. These targets were chosen based on 1) “structural” similarities of 2a‐c with other known bleaching herbicides, and 2) the structure activity relationship previously established with analogs of the lead compound 2a . Syntheses of three target compounds were accomplished, two of which involved various transformations and regioselective additions with a pyridine nucleus to afford novel pyridine derivatives. These targets were tested in whole plant assays with the herbicidal data reported.