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Synthesis of isoindolo[1,3]benzoxazine derivatives through intramolecular arylation of N‐ acyliminium ions
Journal Of Heterocyclic ChemistryPeer ReviewedHucher Nicolas +21998Journals
[1,3]Benzoxazines annulated to isoindole as 3 and 4 have been synthesized in three steps from N ‐chloromethylphthalimide 5 and substituted phenols 6 . The key step was the acid‐catalyzed cyclization of ω‐carbinol lactams 8 and 9.
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