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The reactions of heterocyclic isothiocyanates bearing an ortho ester group with aminoalcohols
Author(s) -
Urleb Uroš
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350331
Subject(s) - chemistry , pteridine , pyrimidine , thiourea , ring (chemistry) , group (periodic table) , stereochemistry , acetonitriles , medicinal chemistry , organic chemistry , enzyme , acetonitrile
Heterocyclic isothiocyanates 1,5,9 , bearing an o ‐ester group were converted to thiourea derivatives 2a‐c, 6a‐b , and 10a‐b , respectively, using β‐aminoalcohols, and to the fused ring systems, e.g ., thieno[3,2‐d]pyrimidine 4a‐b , pyrido[2,3‐ d ]pyrimidine 8 , pteridine 11a , thiazolo[3,2‐ a ]pyrido[2,3‐ d ]pyrimidine 7a‐b , and thiazolo[3,2‐ a ]mieno[3,2‐ d ]pyrirnidine 3a‐c , derivatives.
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