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1,3‐cyclohexanedione as the precursor of C4X‐C6‐C4Y systems. Synthesis of pyrrolo[2,3‐ e ]indoles and thieno[2,3‐ e ]indoles
Author(s) -
Martínez Roberto,
Oloarte Juan Sandoval,
Avila Gustavo
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350315
Subject(s) - chemistry , ketone , diketone , stereochemistry , combinatorial chemistry , organic chemistry
A novel synthesis of substituted pyrrolo[2,3‐ e ]indoles and thieno[2,3‐ e ]indoles is described. This new approach uses 1,3‐cyclohexanedione as the starting material. Diketone intermediates are obtained in four steps from the aforementioned ketone. Using these intermediates, the title compounds are synthesized efficiently.