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Synthesis of novel pyrrolidin‐2‐ones: γ‐aminobutyric acid cyclic analogues
Author(s) -
Ebrik S. Al Akoum,
Rigo B.,
Vaccher C.,
Vaccher MP.,
Flouquet N.,
Debaert M.,
Berthelot P.
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350314
Subject(s) - chemistry , furan , aminobutyric acid , stereochemistry , baclofen , organic chemistry , biochemistry , agonist , receptor
Some new N ‐substituted pyrrolidin‐2‐ones, cyclic analogues of baclofen and of 3‐(5‐methoxybenzo‐[ b ]furan‐2‐yl)‐γ‐aminobutyric acid, have been prepared and characterized, starting from 4‐(4‐chlorophenyl)‐pyrrolidin‐2‐one and 4‐(5‐methoxybenzo[ b ]furan‐2‐yl)pyrrolidin‐2‐one.