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New isomeric N ‐substituted hydrazones of 2‐, 3‐and 4‐pyridinecarboxaldehydes
Author(s) -
Wyrzykiewicz Elżbieta,
Prukała Dorota
Publication year - 1998
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570350221
Subject(s) - chemistry , conformational isomerism , amide , sulfoxide , dimethyl sulfoxide , hydrazone , medicinal chemistry , stereochemistry , organic chemistry , molecule
Eighteen compounds unknown in the literature, N‐(E )‐stilbenyloxyalkylcarbonyl‐ and N‐(E )‐stilbenyloxyalkylcarbonylaminoalkylcarbonyl‐substituted hydrazones of 2‐, 3‐ and 4‐pyridinecarboxaldehydes have been prepared. The stereochemical behavior of these compounds in dimethyl‐d 6 sulfoxide solution has been studied by 1 H‐nmr technique. The E geometrical isomers and cisltrans amide conformers have been found for N ‐substituted‐hydrazones 1–16 .