A new preparation of substituted 4 H ‐1‐benzothiopyran‐4‐ones from c(α) N ‐benzoylhydrazones or c(α) N ‐carboalkoxyhydrazones and methyl thiosalicylate | Zendy

French Kristen L. | Zendy; Angel April J. | Zendy; Williams Angela R. | Zendy; Hurst Douglas R. | Zendy; Beam Charles F. | Zendy

Premium

A new preparation of substituted 4 H ‐1‐benzothiopyran‐4‐ones from c(α) N ‐benzoylhydrazones or c(α) N ‐carboalkoxyhydrazones and methyl thiosalicylate

Author(s) -

French Kristen L.,

Angel April J.,

Williams Angela R.,

Hurst Douglas R.,

Beam Charles F.

Publication year - 1998

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570350109

Subject(s) - lithium diisopropylamide , chemistry , hydrolysis , medicinal chemistry , lithium (medication) , organic chemistry , ion , deprotonation , medicine , endocrinology

C(α) N ‐Benzoylhydrazones or C(α), N ‐carboalkoxyhydrazones were dilithiated with excess lithium diisopropylamide, and the dianion‐type intermediates were condensed with lithiated methyl thiosalicylate, followed by cyclization/hydrolysis to substituted 4 H ‐1‐benzothiopyran‐4‐ones (thioflavones/thiochromones).

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research