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Synthesis and spectral properties of 2,3‐dihydro‐4‐( para ‐substituted‐phenyl)‐7‐[( o ‐, m ‐, and p ‐substituted)phenoxy]‐1 H ‐1,5‐benzodi‐azepine‐2‐thiones
Author(s) -
Cortés Eduardo CortÉS,
Castrejón Carlos M. Alcocer
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340628
Subject(s) - chemistry , spectral properties , medicinal chemistry , stereochemistry , proton nmr , computational chemistry
A series of twelve new 2,3‐dihydro‐4‐( para ‐substituted‐phenyl)‐7‐[( o ‐, m‐ , and p ‐substituted)phenoxy]‐1 H ‐1,5‐benzodiazepine‐2‐thiones, which have potentially useful pharmacological properties, has been synthesized by condensing the 3,3‐dimercapto‐1‐( para ‐substituted phenyl)‐2‐propen‐1‐one with 3,4‐diaminophenyl‐ R ‐phenyl ethers. The structure of all products was corroborated by ir, 1 H‐nmr, 13 C‐nmr and ms.