z-logo
Premium
The synthesis and transformation of ethyl 2‐(2‐acetyl‐2‐benzoyl‐1‐ethenyl)amino‐3‐dimethylaminopropenoate. A new synthesis of 2,3,4‐trisubstituted pyrroles
Author(s) -
Malešič Mateja,
Krbavčič Aleš,
Golobič Amalija,
Golič Ljubo,
Stanovnik Branko
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340619
Subject(s) - chemistry , transformation (genetics) , medicinal chemistry , organic chemistry , stereochemistry , biochemistry , gene
The synthesis of ethyl 2‐(2‐acetyl‐2‐benzoyl‐1‐ethenyl)amino‐3‐dimethylarninopropenoate ( 4 ) from benzoylacetone ( 1 ) via 3‐dimethylarninomethylenebenzoylacetone ( 2 ) and ethyl N ‐(2‐acetyl‐2‐benzoyl‐1‐ethenyl)glycinate ( 3 ) and its transformation into 4‐benzoyl‐2‐ethoxycarbonyl‐3‐methylpyrrole ( 9 ) is described. Cyclization of 4 into 9 represents a new synthesis of polysubstituted pyrroles.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom