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Pyridazines. 84 . Pyridazino[3,4‐ e ]pyrido[3,2‐ b ][1,4]diazepine, a novel tricyclic ring system
Author(s) -
Heinisch Gottfried,
Matuszczak Barbara
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340508
Subject(s) - diazepine , chemistry , tricyclic , ring (chemistry) , pyridazine , stereochemistry , organic chemistry
The preparation of pyridazino[3,4‐ e ]pyrido[3,2‐ b ][1,4]diazepin‐5‐ones 8 and 9 starting from appropriately substituted pyridazine‐4‐carboxamides is reported. The new compounds were tested for HIV‐1 reverse transcriptase inhibitory activity.