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Reaction of N 1 ‐acylacetamidrazones with trifluoroacetylvinyl ethers. Synthesis of new 4‐trifluoromethyl‐ and 6‐trifluoromethylpyridines
Author(s) -
Cocco Maria Teresa,
Congiu Cenzo,
Onnis Valentina,
Bernard Angela Maria,
Piras Pier Paolo
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340432
Subject(s) - chemistry , trifluoromethyl , enol ether , ether , enol , substitution (logic) , medicinal chemistry , organic chemistry , catalysis , alkyl , computer science , programming language
The reaction between N 1 ‐acylacetamidrazones 1 and enol ether 2 is described. Depending on the reaction conditions and on the substitution pattern of amidrazones 2‐acylhydrazino‐4‐methyl‐6‐trifluoro‐methylpyridines 3 and/or 2‐acylhydrazino‐6‐methyl‐4‐trifluoromethylpyridines 4 were obtained.