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Preparation and NMR spectra of substituted 2‐phenyl‐5,5‐dialkylimidazolinones
Author(s) -
Sedlák Miloš,
Halama Aleš,
Mitaš Petr,
Kaválek Jaromír,
Macháček Vladimír
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340421
Subject(s) - chemistry , trifluoroacetic acid , protonation , nmr spectra database , spectral line , boiling , sulfoxide , medicinal chemistry , nuclear magnetic resonance spectroscopy , carbon 13 nmr , dimethyl sulfoxide , organic chemistry , ion , physics , astronomy
Eighteen substituted 2‐phenyl‐5,5‐dialkylimidazolinones 2 have been prepared by cyclizations of substituted 2‐( N ‐benzoylamino)alkanamides 1. The cyclization of methylamides 1 proceeds at room temperature whereas primary amides are cyclized on boiling. The 1 H and 13 C nmr spectra of the imidazolinones are presented and the changes in their spectra connected with their protonation in hexadeuteriodimethyl sulfoxide‐trifluoroacetic acid mixtures are discussed.