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Synthesis of new hetero[2,1]benzothiazepine derivatives
Author(s) -
Vega Salvador,
Díaz Juan A.
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340416
Subject(s) - chemistry , ring (chemistry) , stereochemistry , combinatorial chemistry , organic chemistry
As part of an investigation directed to the search of new neurotropic agents we have prepared a number of hydroxy and hydroximino derivatives of the novel thieno and pyrazolo[2,1]benzothiazepine ring systems. Assignments of the Z and E hydroximino isomers were performed by study of their 1 H and 13 C nmr spectra and NOE experiments.