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A two‐step synthesis of diaminofurazan and synthesis of N ‐monoarylmethyl and N,N ′‐diarylmethyl derivatives
Author(s) -
Zelenin Alexander K.,
Trudell Mark L.
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340355
Subject(s) - chemistry , glyoxal , alkylation , aryl , medicinal chemistry , organic chemistry , catalysis , alkyl
Diaminofurazan (1) was synthesized from glyoxal (2) by an improved two‐step procedure. The N ‐mono‐arylmethyl derivatives 4a‐e and N‐N' ‐diarylmethyl derivatives 5a‐e of 1 were prepared in good yields by reductive alkylation with the corresponding aryl aldehydes.