The synthesis of azahomotryptophane derivatives. The transformation of  N ‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl ester into 4‐(imidazo[1,2‐ a ]azinyl‐3)‐4‐oxohomoalanine derivatives | Zendy

Škof Marko | Zendy; Svete Jurij | Zendy; Stanovnik Branko | Zendy

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The synthesis of azahomotryptophane derivatives. The transformation of N ‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl ester into 4‐(imidazo[1,2‐ a ]azinyl‐3)‐4‐oxohomoalanine derivatives

Author(s) -

Škof Marko,

Svete Jurij,

Stanovnik Branko

Publication year - 1997

Publication title -

journal of heterocyclic chemistry

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.321

H-Index - 59

eISSN - 1943-5193

pISSN - 0022-152X

DOI - 10.1002/jhet.5570340323

Subject(s) - chemistry , medicinal chemistry , transformation (genetics) , stereochemistry , biochemistry , gene

Azatryptophane homologues, 4‐(imidazo[1,2‐ a ]pyridinyl‐3)‐ 9a‐9f and 4‐(imidazo[1,2‐ a ]pyrimidinyl‐3)‐4‐oxohomoalanine derivatives 9g‐91 , were prepared from N,N ‐dimethyl‐ N ′‐(pyridinyl‐2)‐ 6a‐6f and N,N ‐dimethyl‐ N ‐(pyriniidinyl‐2)formamidines 6g‐6i , and ( S )‐ N ‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl ester ( 2 ) and its ( R,S )‐isomer.

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