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The synthesis of azahomotryptophane derivatives. The transformation of N ‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl ester into 4‐(imidazo[1,2‐ a ]azinyl‐3)‐4‐oxohomoalanine derivatives
Author(s) -
Škof Marko,
Svete Jurij,
Stanovnik Branko
Publication year - 1997
Publication title -
journal of heterocyclic chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.321
H-Index - 59
eISSN - 1943-5193
pISSN - 0022-152X
DOI - 10.1002/jhet.5570340323
Subject(s) - chemistry , medicinal chemistry , transformation (genetics) , stereochemistry , biochemistry , gene
Azatryptophane homologues, 4‐(imidazo[1,2‐ a ]pyridinyl‐3)‐ 9a‐9f and 4‐(imidazo[1,2‐ a ]pyrimidinyl‐3)‐4‐oxohomoalanine derivatives 9g‐91 , were prepared from N,N ‐dimethyl‐ N ′‐(pyridinyl‐2)‐ 6a‐6f and N,N ‐dimethyl‐ N ‐(pyriniidinyl‐2)formamidines 6g‐6i , and ( S )‐ N ‐trifluoroacetyl‐5‐bromo‐4‐oxonorvaline methyl ester ( 2 ) and its ( R,S )‐isomer.